Cargando…

Nose-to-brain delivery of borneol modified tanshinone IIA nanoparticles in prevention of cerebral ischemia/reperfusion injury

Targeted treatment of cerebral ischemia/reperfusion injury (CIRI) remains a problem due to the difficulty in drug delivery across the blood–brain barrier (BBB). In this study, we developed Bo-TSA-NP, a novel tanshinone IIA (TSA) loaded nanoparticles modified by borneol, which has long been proved wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Luting, Xu, Lin, Du, Junfeng, Zhao, Xiao, Liu, Mei, Feng, Jianfang, Hu, Kaili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245080/ https://www.ncbi.nlm.nih.gov/pubmed/34180761 http://dx.doi.org/10.1080/10717544.2021.1943058

Ejemplares similares

Protective effect of tanshinone IIA on the brain and its therapeutic time window in rat models of cerebral ischemia-reperfusion
por: TANG, QIQIANG, et al.
Publicado: (2014)

Neuroprotection of Tanshinone IIA against Cerebral Ischemia/Reperfusion Injury through Inhibition of Macrophage Migration Inhibitory Factor in Rats
por: Chen, Yanlin, et al.
Publicado: (2012)

Modified Lipid Nanocapsules for Targeted Tanshinone IIA Delivery in Liver Fibrosis
por: Ashour, Asmaa A, et al.
Publicado: (2021)

Protective effects of tanshinone IIA sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats
por: Pan, Yun, et al.
Publicado: (2017)

Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats
por: Tai, He, et al.
Publicado: (2022)

Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats
por: Tai, He, et al.
Publicado: (2021)

Effect of tanshinone IIA for myocardial ischemia/reperfusion injury in animal model: preclinical evidence and possible mechanisms
por: Zhu, Peng-Chong, et al.
Publicado: (2023)

Tanshinone IIA Protects Against Cerebral Ischemia Reperfusion Injury by Regulating Microglial Activation and Polarization via NF-κB Pathway
por: Song, Zhibing, et al.
Publicado: (2021)

Preparation, Characterization and in vivo Study of Borneol-Baicalin-Liposomes for Treatment of Cerebral Ischemia-Reperfusion Injury
por: Zhang, Yulu, et al.
Publicado: (2020)

Tanshinone IIA confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis and apoptosis via VDAC1
por: Hu, Tie, et al.
Publicado: (2023)

Preparation of baicalin-loaded ligand-modified nanoparticles for nose-to-brain delivery for neuroprotection in cerebral ischemia
por: Li, Xinxin, et al.
Publicado: (2022)

Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats
por: Tai, He, et al.
Publicado: (2021)

Pharmacological postconditioning with tanshinone IIA attenuates myocardial ischemia-reperfusion injury in rats by activating the phosphatidylinositol 3-kinase pathway
por: YUAN, XUN, et al.
Publicado: (2014)

Design, characterization and comparison of transdermal delivery of colchicine via borneol-chemically-modified and borneol-physically-modified ethosome
por: Zhang, Yujia, et al.
Publicado: (2019)

Synergic Effect of Borneol and Ligustrazine on the Neuroprotection in Global Cerebral Ischemia/Reperfusion Injury: A Region-Specificity Study
por: Yu, Bin, et al.
Publicado: (2016)

Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: An In Vitro Study
por: Chan, Szu-Erh, et al.
Publicado: (2011)

Influence of Tanshinone IIa on heat shock protein 70, Bcl-2 and Bax expression in rats with spinal ischemia/reperfusion injury☆
por: Zhang, Li, et al.
Publicado: (2012)

Galactose-Modified PH-Sensitive Niosomes for Controlled Release and Hepatocellular Carcinoma Target Delivery of Tanshinone IIA
por: Hu, Xixi, et al.
Publicado: (2021)

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones
por: Zhai, Xifeng, et al.
Publicado: (2017)

Simultaneous purification of dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA from Salvia miltiorrhiza and their anti-inflammatory activities investigation
por: Gao, Hongwei, et al.
Publicado: (2018)

Tanshinone IIA ameliorates myocardial ischemia/reperfusion injury in rats by regulation of NLRP3 inflammasome activation and Th17 cells differentiation
por: Li, Dan, et al.
Publicado: (2022)

Evaluation of Tanshinone IIA Developmental Toxicity in Zebrafish Embryos
por: Wang, Tao, et al.
Publicado: (2017)

Preparation, characterization, and in vivo evaluation of tanshinone IIA solid dispersions with silica nanoparticles
por: Jiang, Yan-rong, et al.
Publicado: (2013)

Folate and Borneol Modified Bifunctional Nanoparticles for Enhanced Oral Absorption
por: Yang, Yifan, et al.
Publicado: (2018)

Sodium tanshinone IIA sulfonate ameliorates cerebral ischemic injury through regulation of angiogenesis
por: Xu, Jiazhen, et al.
Publicado: (2021)

Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2012)

Multifunctional icariin and tanshinone IIA co-delivery liposomes with potential application for Alzheimer’s disease
por: Wang, Jiao, et al.
Publicado: (2022)

Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson’s disease
por: Tang, Shengnan, et al.
Publicado: (2019)

(+)-Borneol is neuroprotective against permanent cerebral ischemia in rats by suppressing production of proinflammatory cytokines
por: Chang, Lei, et al.
Publicado: (2017)

Tanshinone IIA: A Promising Natural Cardioprotective Agent
por: Shang, Qinghua, et al.
Publicado: (2012)

Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA
por: Shen, Jui-Lung, et al.
Publicado: (2011)

Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis
por: Chen, Zhuo, et al.
Publicado: (2014)

Characterization and Stability of Tanshinone IIA Solid Dispersions with Hydroxyapatite
por: Wang, Xiaopan, et al.
Publicado: (2013)

Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats
por: Yan, Jun, et al.
Publicado: (2016)

Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases
por: Guo, Rui, et al.
Publicado: (2020)

Tanshinone IIA: A Review of its Anticancer Effects
por: Fang, Zhong‐ying, et al.
Publicado: (2021)

Renoprotective Effects of Tanshinone IIA: A Literature Review
por: Chen, Zhengtao, et al.
Publicado: (2023)

Preparation of gastrodin‐modified dendrimer‐entrapped gold nanoparticles as a drug delivery system for cerebral ischemia–reperfusion injury
por: Huang, Wenqiang, et al.
Publicado: (2022)

Tanshinone IIA attenuates cerebral aneurysm formation by inhibiting the NF-κB-mediated inflammatory response
por: Ma, Jun, et al.
Publicado: (2019)

Inhibitory Effect of Tanshinone IIA on Rat Hepatic Stellate Cells
por: Liu, Ya-Wei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rjuc23kr47namb3a72on9r6c55