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Docetaxel loaded mPEG-PLA nanoparticles for sarcoma therapy: preparation, characterization, pharmacokinetics, and anti-tumor efficacy

Sarcoma represents one of the most common malignant tumors with poor treatment outcomes and prognosis. Docetaxel (DTX) is acknowledged as one of the most important chemotherapy agents. The aim of this study was to improve the efficacy of docetaxel by incorporation into the mPEG-PLA nanoparticle (DTX...

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Detalles Bibliográficos
Autores principales: Chen, Jianhua, Ning, Eerdunbagena, Wang, Zhijun, Jing, Ziqi, Wei, Guijie, Wang, Xue, Ma, Pengkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245084/
https://www.ncbi.nlm.nih.gov/pubmed/34180752
http://dx.doi.org/10.1080/10717544.2021.1945167