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Novel Use of Extracorporeal Blood Purification for Treatment of Severe, Refractory Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy—A Case Report

BACKGROUND: Chimeric antigen receptor T-cell therapies (CAR-T) are transforming the treatment of B-cell leukemias and lymphomas. Cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome represent common, potentially life-threatening toxicities from chimeric antigen recept...

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Detalles Bibliográficos
Autores principales: Singbartl, Kai, Rosenthal, Allison, Leis, Jose, Patel, Bhavesh, Sen, Ayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245117/
https://www.ncbi.nlm.nih.gov/pubmed/34235458
http://dx.doi.org/10.1097/CCE.0000000000000472