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The Ca(2+)-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

Pathological left ventricular hypertrophy (LVH) occurs in response to pressure overload and remains the single most important clinical predictor of cardiac mortality. The molecular pathways in the induction of pressure overload LVH are potential targets for therapeutic intervention. Current treatmen...

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Detalles Bibliográficos
Autores principales: Guo, Yang, Yu, Ze-Yan, Wu, Jianxin, Gong, Hutao, Kesteven, Scott, Iismaa, Siiri E, Chan, Andrea Y, Holman, Sara, Pinto, Silvia, Pironet, Andy, Cox, Charles D, Graham, Robert M, Vennekens, Rudi, Feneley, Michael P, Martinac, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245133/
https://www.ncbi.nlm.nih.gov/pubmed/34190686
http://dx.doi.org/10.7554/eLife.66582