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Loss of Function of von Hippel-Lindau Trigger Lipocalin 2-Dependent Inflammatory Responses in Cultured and Primary Renal Tubular Cells

Previous studies have shown that mutations in the tumor suppressor gene von Hippel-Lindau (VHL) can result in the overproduction of reactive oxygen species (ROS) and chronic inflammation and are a significant predisposing factor for the development of clear-cell renal cell carcinoma (ccRCC). To stud...

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Detalles Bibliográficos
Autores principales: Kuo, Chan-Yen, Chiu, Valeria, Hsieh, Po-Chun, Hsu, Tien, Lin, Ting-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245224/
https://www.ncbi.nlm.nih.gov/pubmed/34257811
http://dx.doi.org/10.1155/2021/5571638