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Functional ACE2 deficiency leading to angiotensin imbalance in the pathophysiology of COVID-19
SARS-CoV-2, the virus responsible for COVID-19, uses angiotensin converting enzyme 2 (ACE2) as its primary cell-surface receptor. ACE2 is a key enzyme in the counter-regulatory pathway of the broader renin-angiotensin system (RAS) that has been implicated in a broad array of human pathology. The RAS...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245275/ https://www.ncbi.nlm.nih.gov/pubmed/34195965 http://dx.doi.org/10.1007/s11154-021-09663-z |