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Observed and expected serious adverse event rates in randomised clinical trials for hypertension: an observational study comparing trials that do and do not focus on older people

BACKGROUND: Representativeness of antihypertensive drug trials is uncertain, as many trials recruit few or no older people. Some trials specifically recruit older participants to address this. Here, we assess the representativeness of trials focusing on older people by comparing the rates of serious...

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Detalles Bibliográficos
Autores principales: Hanlon, Peter, Corcoran, Neave, Rughani, Guy, Shah, Anoop S V, Mair, Frances S, Guthrie, Bruce, Renton, Joanne P, McAllister, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245327/
https://www.ncbi.nlm.nih.gov/pubmed/34240062
http://dx.doi.org/10.1016/S2666-7568(21)00092-1