SN38 loaded nanostructured lipid carriers (NLCs); preparation and in vitro evaluations against glioblastoma

SN38 is the active metabolite of irinotecan with 1000-fold greater cytotoxicity compared to the parent drug. Despite the potential, its application as a drug is still seriously limited due to its stability concerns and low solubility in acceptable pharmaceutical solvents. To address these drawbacks...

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Detalles Bibliográficos
Autores principales: Shirazi, Ali Sabouri, Varshochian, Reyhaneh, Rezaei, Mahsa, Ardakani, Yalda Hosseinzadeh, Dinarvand, Rassoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Delivery Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245372/
https://www.ncbi.nlm.nih.gov/pubmed/34191134
http://dx.doi.org/10.1007/s10856-021-06538-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245372/
https://www.ncbi.nlm.nih.gov/pubmed/34191134
http://dx.doi.org/10.1007/s10856-021-06538-2

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