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SN38 loaded nanostructured lipid carriers (NLCs); preparation and in vitro evaluations against glioblastoma
SN38 is the active metabolite of irinotecan with 1000-fold greater cytotoxicity compared to the parent drug. Despite the potential, its application as a drug is still seriously limited due to its stability concerns and low solubility in acceptable pharmaceutical solvents. To address these drawbacks...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245372/ https://www.ncbi.nlm.nih.gov/pubmed/34191134 http://dx.doi.org/10.1007/s10856-021-06538-2 |