A Phase 1 Study to Evaluate the Drug Interaction Between Islatravir (MK-8591) and Doravirine in Adults Without HIV

BACKGROUND AND OBJECTIVES: Islatravir (MK-8591) is a novel nucleoside analogue in development for the treatment and prevention of HIV-1 infection. Doravirine is a non-nucleoside reverse transcriptase inhibitor indicated for the treatment of HIV-1 infection. This study evaluated the pharmacokinetics,...

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Detalles Bibliográficos
Autores principales: Matthews, Randolph P., Jackson Rudd, Deanne, Fillgrove, Kerry L., Zhang, Saijuan, Tomek, Charles, Stoch, S. Aubrey, Iwamoto, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245385/
https://www.ncbi.nlm.nih.gov/pubmed/34151413
http://dx.doi.org/10.1007/s40261-021-01046-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245385/
https://www.ncbi.nlm.nih.gov/pubmed/34151413
http://dx.doi.org/10.1007/s40261-021-01046-1

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