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Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers

AIMS/HYPOTHESIS: The common muscle-specific TBC1D4 p.Arg684Ter loss-of-function variant defines a subtype of non-autoimmune diabetes in Arctic populations. Homozygous carriers are characterised by elevated postprandial glucose and insulin levels. Because 3.8% of the Greenlandic population are homozy...

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Detalles Bibliográficos
Autores principales: Schnurr, Theresia M., Jørsboe, Emil, Chadt, Alexandra, Dahl-Petersen, Inger K., Kristensen, Jonas M., Wojtaszewski, Jørgen F. P., Springer, Christian, Bjerregaard, Peter, Brage, Søren, Pedersen, Oluf, Moltke, Ida, Grarup, Niels, Al-Hasani, Hadi, Albrechtsen, Anders, Jørgensen, Marit E., Hansen, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245392/
https://www.ncbi.nlm.nih.gov/pubmed/33912980
http://dx.doi.org/10.1007/s00125-021-05461-z