Auranofin prevents liver fibrosis by system Xc-mediated inhibition of NLRP3 inflammasome

Demand for a cure of liver fibrosis is rising with its increasing morbidity and mortality. Therefore, it is an urgent issue to investigate its therapeutic candidates. Liver fibrosis progresses following ‘multi-hit’ processes involving hepatic stellate cells, macrophages, and hepatocytes. The NOD-lik...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Young, Choi, Young Jae, Kim, Sang Kyum, Kim, Hyunsung, Jun, Dae Won, Yoon, Kyungrok, Kim, Nayoun, Hwang, Jungwook, Kim, Young-Mi, Lim, Sung Chul, Kang, Keon Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245406/
https://www.ncbi.nlm.nih.gov/pubmed/34193972
http://dx.doi.org/10.1038/s42003-021-02345-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245406/
https://www.ncbi.nlm.nih.gov/pubmed/34193972
http://dx.doi.org/10.1038/s42003-021-02345-1

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