A DL-4- and TNFα-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors

Several obstacles to the production, expansion and genetic modification of immunotherapeutic T cells in vitro have restricted the widespread use of T-cell immunotherapy. In the context of HSCT, delayed naïve T-cell recovery contributes to poor outcomes. A novel approach to overcome the major limitat...

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Detalles Bibliográficos
Autores principales: Moirangthem, Ranjita Devi, Ma, Kuiying, Lizot, Sabrina, Cordesse, Anne, Olivré, Juliette, de Chappedelaine, Corinne, Joshi, Akshay, Cieslak, Agata, Tchen, John, Cagnard, Nicolas, Asnafi, Vahid, Rausell, Antonio, Simons, Laura, Zuber, Julien, Taghon, Tom, Staal, Frank J. T., Pflumio, Françoise, Six, Emmanuelle, Cavazzana, Marina, Lagresle-Peyrou, Chantal, Soheili, Tayebeh, André, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245454/
https://www.ncbi.nlm.nih.gov/pubmed/34117371
http://dx.doi.org/10.1038/s41423-021-00706-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245454/
https://www.ncbi.nlm.nih.gov/pubmed/34117371
http://dx.doi.org/10.1038/s41423-021-00706-8

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