Dysregulated immunity in PID patients with low GARP expression on Tregs due to mutations in LRRC32

Immune dysregulation diseases are characterized by heterogeneous clinical manifestations and may have severe disease courses. The identification of the genetic causes of these diseases therefore has critical clinical implications. We performed whole-exome sequencing of patients with immune dysregula...

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Detalles Bibliográficos
Autores principales: Lehmkuhl, Peter, Gentz, Magdalena, Garcia de Otezya, Andres Caballero, Grimbacher, Bodo, Schulze-Koops, Hendrik, Skapenko, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245512/
https://www.ncbi.nlm.nih.gov/pubmed/34059789
http://dx.doi.org/10.1038/s41423-021-00701-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245512/
https://www.ncbi.nlm.nih.gov/pubmed/34059789
http://dx.doi.org/10.1038/s41423-021-00701-z

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