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Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide

The permeability barrier of nuclear pore complexes (NPCs) controls nucleocytoplasmic transport. It retains inert macromolecules while allowing facilitated passage of importins and exportins, which in turn shuttle cargo into or out of cell nuclei. The barrier can be described as a condensed phase ass...

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Detalles Bibliográficos
Autores principales: Ng, Sheung Chun, Güttler, Thomas, Görlich, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245513/
https://www.ncbi.nlm.nih.gov/pubmed/34193851
http://dx.doi.org/10.1038/s41467-021-24292-5