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Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide
The permeability barrier of nuclear pore complexes (NPCs) controls nucleocytoplasmic transport. It retains inert macromolecules while allowing facilitated passage of importins and exportins, which in turn shuttle cargo into or out of cell nuclei. The barrier can be described as a condensed phase ass...
Autores principales: | Ng, Sheung Chun, Güttler, Thomas, Görlich, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245513/ https://www.ncbi.nlm.nih.gov/pubmed/34193851 http://dx.doi.org/10.1038/s41467-021-24292-5 |
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