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Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis

Cellular stress can lead to several human disease pathologies due to aberrant cell death. The p53 family (tp53, tp63, and tp73) and downstream transcriptional apoptotic target genes (PUMA/BBC3 and NOXA/PMAIP1) have been implicated as mediators of stress signals. To evaluate the importance of key str...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Thomas, Holly R., Li, Zhang, Yeo, Nan Cher (Florence), Scott, Hannah E., Dang, Nghi, Hossain, Mohammed Iqbal, Andrabi, Shaida A., Parant, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245518/
https://www.ncbi.nlm.nih.gov/pubmed/34193827
http://dx.doi.org/10.1038/s41419-021-03902-6