Cargando…
Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis
Cellular stress can lead to several human disease pathologies due to aberrant cell death. The p53 family (tp53, tp63, and tp73) and downstream transcriptional apoptotic target genes (PUMA/BBC3 and NOXA/PMAIP1) have been implicated as mediators of stress signals. To evaluate the importance of key str...
Autores principales: | Wang, Jun, Thomas, Holly R., Li, Zhang, Yeo, Nan Cher (Florence), Scott, Hannah E., Dang, Nghi, Hossain, Mohammed Iqbal, Andrabi, Shaida A., Parant, John M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245518/ https://www.ncbi.nlm.nih.gov/pubmed/34193827 http://dx.doi.org/10.1038/s41419-021-03902-6 |
Ejemplares similares
-
EWS Knockdown and Taxifolin Treatment Induced Differentiation and Removed DNA Methylation from p53 Promoter to Promote Expression of Puma and Noxa for Apoptosis in Ewing’s Sarcoma
por: Hossain, Mohammad Motarab, et al.
Publicado: (2014) -
BH3-Only Proteins Noxa and Puma Are Key Regulators of Induced Apoptosis
por: Roufayel, Rabih, et al.
Publicado: (2022) -
Expression of Bim, Noxa, and Puma in non-small cell lung cancer
por: Sakakibara-Konishi, Jun, et al.
Publicado: (2012) -
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis
por: Holzerland, Julia, et al.
Publicado: (2020) -
PUMA-mediated apoptosis in fibroblast-like synoviocytes does not require p53
por: You, Xin, et al.
Publicado: (2006)