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Drosophila tubulin polymerization promoting protein mutants reveal pathological correlates relevant to human Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder with no known cure. PD is characterized by locomotion deficits, nigrostriatal dopaminergic neuronal loss, mitochondrial dysfunctions and formation of α-Synuclein aggregates. A well-conserved and less understood family of Tubulin Po...

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Detalles Bibliográficos
Autores principales: Xie, Jing, Chen, Shuting, Bopassa, Jean C., Banerjee, Swati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245532/
https://www.ncbi.nlm.nih.gov/pubmed/34193896
http://dx.doi.org/10.1038/s41598-021-92738-3