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Age-dependent shift in the de novo proteome accompanies pathogenesis in an Alzheimer’s disease mouse model
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder associated with memory loss, but the AD-associated neuropathological changes begin years before memory impairments. Investigation of the early molecular abnormalities in AD might offer innovative opportunities to target memory imp...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245541/ https://www.ncbi.nlm.nih.gov/pubmed/34193971 http://dx.doi.org/10.1038/s42003-021-02324-6 |