Neoantigens elicit T cell responses in breast cancer

Neoantigens are tumour-specific antigens that arise from non-synonymous mutations in tumour cells. However, their effect on immune responses in the tumour microenvironment remains unclear in breast cancer. We performed whole exome and RNA sequencing of 31 fresh breast cancer tissues and neoantigen p...

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Detalles Bibliográficos
Autores principales: Morisaki, Takafumi, Kubo, Makoto, Umebayashi, Masayo, Yew, Poh Yin, Yoshimura, Sachiko, Park, Jae-Hyun, Kiyotani, Kazuma, Kai, Masaya, Yamada, Mai, Oda, Yoshinao, Nakamura, Yusuke, Morisaki, Takashi, Nakamura, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245657/
https://www.ncbi.nlm.nih.gov/pubmed/34193879
http://dx.doi.org/10.1038/s41598-021-91358-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245657/
https://www.ncbi.nlm.nih.gov/pubmed/34193879
http://dx.doi.org/10.1038/s41598-021-91358-1

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