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RAS Nanoclusters Selectively Sort Distinct Lipid Headgroups and Acyl Chains
RAS proteins are lipid-anchored small GTPases that switch between the GTP-bound active and GDP-bound inactive states. RAS isoforms, including HRAS, NRAS and splice variants KRAS4A and KRAS4B, are some of the most frequently mutated proteins in cancer. In particular, constitutively active mutants of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245699/ https://www.ncbi.nlm.nih.gov/pubmed/34222339 http://dx.doi.org/10.3389/fmolb.2021.686338 |