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The Ca(2+)-activated chloride channel ANO1/TMEM16A: An emerging therapeutic target for epithelium-originated diseases?

Anoctamin 1 (ANO1) or TMEM16A gene encodes a member of Ca(2+) activated Cl(–) channels (CaCCs) that are critical for physiological functions, such as epithelial secretion, smooth muscle contraction and sensory signal transduction. The attraction and interest in ANO1/TMEM16A arise from a decade long...

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Detalles Bibliográficos
Autores principales: Liu, Yani, Liu, Zongtao, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245819/
https://www.ncbi.nlm.nih.gov/pubmed/34221860
http://dx.doi.org/10.1016/j.apsb.2020.12.003