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The Ca(2+)-activated chloride channel ANO1/TMEM16A: An emerging therapeutic target for epithelium-originated diseases?
Anoctamin 1 (ANO1) or TMEM16A gene encodes a member of Ca(2+) activated Cl(–) channels (CaCCs) that are critical for physiological functions, such as epithelial secretion, smooth muscle contraction and sensory signal transduction. The attraction and interest in ANO1/TMEM16A arise from a decade long...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245819/ https://www.ncbi.nlm.nih.gov/pubmed/34221860 http://dx.doi.org/10.1016/j.apsb.2020.12.003 |