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Notoginsenoside Ft1 acts as a TGR5 agonist but FXR antagonist to alleviate high fat diet-induced obesity and insulin resistance in mice

Obesity and its associated complications are highly related to a current public health crisis around the world. A growing body of evidence has indicated that G-protein coupled bile acid (BA) receptor TGR5 (also known as Gpbar-1) is a potential drug target to treat obesity and associated metabolic di...

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Detalles Bibliográficos
Autores principales: Ding, Lili, Yang, Qiaoling, Zhang, Eryun, Wang, Yangmeng, Sun, Siming, Yang, Yingbo, Tian, Tong, Ju, Zhengcai, Jiang, Linshan, Wang, Xunjiang, Wang, Zhengtao, Huang, Wendong, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245856/
https://www.ncbi.nlm.nih.gov/pubmed/34221867
http://dx.doi.org/10.1016/j.apsb.2021.03.038