Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats

Transcellular permeation enhancers are known to increase the intestinal permeability of enalaprilat, a 349 Da peptide, but not hexarelin (887 Da). The primary aim of this paper was to investigate if paracellular permeability enhancers affected the intestinal permeation of the two peptides. This was...

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Detalles Bibliográficos
Autores principales: Dahlgren, David, Olander, Tobias, Sjöblom, Markus, Hedeland, Mikael, Lennernäs, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245904/
https://www.ncbi.nlm.nih.gov/pubmed/34221875
http://dx.doi.org/10.1016/j.apsb.2020.12.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245904/
https://www.ncbi.nlm.nih.gov/pubmed/34221875
http://dx.doi.org/10.1016/j.apsb.2020.12.019

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