Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation

BACKGROUND: Disruption of DNA methylation (DNAm) is one of the key signatures of cancer, however, detailed mechanisms that alter the DNA methylome in cancer remain to be elucidated. METHODS: Here we present a novel integrative analysis framework, called MeLncTRN (Methylation mediated LncRNA Transcri...

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Detalles Bibliográficos
Autores principales: Yang, Zhen, Xu, Feng, Wang, Haizhou, Teschendorff, Andrew E, Xie, Feng, He, Yungang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245911/
https://www.ncbi.nlm.nih.gov/pubmed/34044218
http://dx.doi.org/10.1016/j.ebiom.2021.103399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245911/
https://www.ncbi.nlm.nih.gov/pubmed/34044218
http://dx.doi.org/10.1016/j.ebiom.2021.103399

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