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Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation
BACKGROUND: Disruption of DNA methylation (DNAm) is one of the key signatures of cancer, however, detailed mechanisms that alter the DNA methylome in cancer remain to be elucidated. METHODS: Here we present a novel integrative analysis framework, called MeLncTRN (Methylation mediated LncRNA Transcri...
Autores principales: | Yang, Zhen, Xu, Feng, Wang, Haizhou, Teschendorff, Andrew E, Xie, Feng, He, Yungang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245911/ https://www.ncbi.nlm.nih.gov/pubmed/34044218 http://dx.doi.org/10.1016/j.ebiom.2021.103399 |
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