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NPC1 regulates the distribution of phosphatidylinositol 4‐kinases at Golgi and lysosomal membranes

Cholesterol and phosphoinositides (PI) are two critically important lipids that are found in cellular membranes and dysregulated in many disorders. Therefore, uncovering molecular pathways connecting these essential lipids may offer new therapeutic insights. We report that loss of function of lysoso...

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Detalles Bibliográficos
Autores principales: Kutchukian, Candice, Vivas, Oscar, Casas, Maria, Jones, Julia G, Tiscione, Scott A, Simó, Sergi, Ory, Daniel S, Dixon, Rose E, Dickson, Eamonn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246069/
https://www.ncbi.nlm.nih.gov/pubmed/34019311
http://dx.doi.org/10.15252/embj.2020105990