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NPC1 regulates the distribution of phosphatidylinositol 4‐kinases at Golgi and lysosomal membranes
Cholesterol and phosphoinositides (PI) are two critically important lipids that are found in cellular membranes and dysregulated in many disorders. Therefore, uncovering molecular pathways connecting these essential lipids may offer new therapeutic insights. We report that loss of function of lysoso...
Autores principales: | Kutchukian, Candice, Vivas, Oscar, Casas, Maria, Jones, Julia G, Tiscione, Scott A, Simó, Sergi, Ory, Daniel S, Dixon, Rose E, Dickson, Eamonn J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246069/ https://www.ncbi.nlm.nih.gov/pubmed/34019311 http://dx.doi.org/10.15252/embj.2020105990 |
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