An engineered biosynthetic–synthetic platform for production of halogenated indolmycin antibiotics

Indolmycin is an antibiotic from Streptomyces griseus ATCC 12648 with activity against Helicobacter pylori, Plasmodium falciparum, and methicillin-resistant Staphylococcus aureus. Here we describe the use of the indolmycin biosynthetic genes in E. coli to make indolmycenic acid, a chiral intermediat...

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Detalles Bibliográficos
Autores principales: Hoffarth, Elesha R., Kong, Sunnie, He, Hai-Yan, Ryan, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246080/
https://www.ncbi.nlm.nih.gov/pubmed/34257882
http://dx.doi.org/10.1039/d0sc05843b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246080/
https://www.ncbi.nlm.nih.gov/pubmed/34257882
http://dx.doi.org/10.1039/d0sc05843b

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