Cargando…

Programmed −1 ribosomal frameshifting from the perspective of the conformational dynamics of mRNA and ribosomes

Programmed −1 ribosomal frameshifting (−1 PRF) is a translation mechanism that regulates the relative expression level of two proteins encoded on the same messenger RNA (mRNA). This regulation is commonly used by viruses such as coronaviruses and retroviruses but rarely by host human cells, and for...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Kai-Chun, Wen, Jin-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246090/
https://www.ncbi.nlm.nih.gov/pubmed/34257837
http://dx.doi.org/10.1016/j.csbj.2021.06.015