Collagen triple helix repeat containing-1 exerts antifibrotic effects on human skin fibroblast and bleomycin-induced dermal fibrosis models

BACKGROUND: Systemic scleroderma (SSc) is an acquired disorder characterized by excessive deposition of extracellular matrix in the skin and internal organs. So far, the molecular mechanisms underpinning the pathogenesis of SSc have remained unknown. Collagen triple helix repeat containing-1 (CTHRC1...

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Detalles Bibliográficos
Autores principales: Shen, Zhu, Su, Tangfeng, Chen, Jin, Xie, Zhen, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246160/
https://www.ncbi.nlm.nih.gov/pubmed/34268414
http://dx.doi.org/10.21037/atm-21-1884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246160/
https://www.ncbi.nlm.nih.gov/pubmed/34268414
http://dx.doi.org/10.21037/atm-21-1884

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