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PRMT5 inhibition modulates murine dendritic cells activation by inhibiting the metabolism switch: a new therapeutic target in periodontitis

BACKGROUND: Protein arginine methyltransferase 5 (PRMT5) catalyzes the methylation of arginine residues in multiple proteins. Recent reports have highlighted the anti-inflammatory role of PRMT5. Dendritic cells (DCs) are well-known professional antigen-presenting cells that are crucial for immune re...

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Detalles Bibliográficos
Autores principales: Mi, Wenxiang, Qiao, Shichong, Zhang, Xiaomeng, Wu, Dongle, Zhou, Linyi, Lai, Hongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246170/
https://www.ncbi.nlm.nih.gov/pubmed/34268368
http://dx.doi.org/10.21037/atm-20-7362