Diabetes mellitus accelerates the progression of osteoarthritis in streptozotocin-induced diabetic mice by deteriorating bone microarchitecture, bone mineral composition, and bone strength of subchondral bone

BACKGROUND: The purpose of this study was to develop an optimal diabetes-osteoarthritis (DM-OA) mouse model to validate that diabetes aggravates osteoarthritis (OA) and to evaluate the microarchitecture, chemical composition, and biomechanical properties of subchondral bone (SB) as a consequence of...

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Detalles Bibliográficos
Autores principales: Wang, Hua-Jun, Giambini, Hugo, Chen, Ji-Wen, Wang, Qiu-Shi, Hou, Hui-Ge, Luo, Si-Min, Chen, Jun-Yuan, Zhuang, Teng-Feng, Chen, Yuan-Feng, Wu, Ting-Ting, Zha, Zhen-Gang, Liu, You-Jie, Zheng, Xiao-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246216/
https://www.ncbi.nlm.nih.gov/pubmed/34268381
http://dx.doi.org/10.21037/atm-20-6797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246216/
https://www.ncbi.nlm.nih.gov/pubmed/34268381
http://dx.doi.org/10.21037/atm-20-6797

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