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Diabetes mellitus accelerates the progression of osteoarthritis in streptozotocin-induced diabetic mice by deteriorating bone microarchitecture, bone mineral composition, and bone strength of subchondral bone
BACKGROUND: The purpose of this study was to develop an optimal diabetes-osteoarthritis (DM-OA) mouse model to validate that diabetes aggravates osteoarthritis (OA) and to evaluate the microarchitecture, chemical composition, and biomechanical properties of subchondral bone (SB) as a consequence of...
Autores principales: | Wang, Hua-Jun, Giambini, Hugo, Chen, Ji-Wen, Wang, Qiu-Shi, Hou, Hui-Ge, Luo, Si-Min, Chen, Jun-Yuan, Zhuang, Teng-Feng, Chen, Yuan-Feng, Wu, Ting-Ting, Zha, Zhen-Gang, Liu, You-Jie, Zheng, Xiao-Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246216/ https://www.ncbi.nlm.nih.gov/pubmed/34268381 http://dx.doi.org/10.21037/atm-20-6797 |
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