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Exosomes derived from cyclic mechanical stretch-exposed bone marrow mesenchymal stem cells inhibit RANKL-induced osteoclastogenesis through the NF-κB signaling pathway

BACKGROUND: Skeletal unloading usually induces severe disuse osteoporosis (DOP), which often occurs in patients subjected to prolonged immobility or in spaceflight astronauts. Increasing evidence suggests that exosomes are important mediators in maintaining the balance between bone formation and res...

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Zuo, Bin, Tao, Bo, Wang, Chuandong, Li, Yang, Peng, Jianping, Shen, Chao, Cui, Yiming, Zhu, Junfeng, Chen, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246225/
https://www.ncbi.nlm.nih.gov/pubmed/34268411
http://dx.doi.org/10.21037/atm-21-1838