Cargando…
Dual roles of HSP70 chaperone HSPA1 in quality control of nascent and newly synthesized proteins
Exposure to heat stress triggers a well‐defined acute response marked by HSF1‐dependent transcriptional upregulation of heat shock proteins. Cells allowed to recover acquire thermotolerance, but this adaptation is poorly understood. By quantitative proteomics, we discovered selective upregulation of...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246255/ https://www.ncbi.nlm.nih.gov/pubmed/34010456 http://dx.doi.org/10.15252/embj.2020106183 |