Zebrafish mbnl mutants model physical and molecular phenotypes of myotonic dystrophy

The muscleblind RNA-binding proteins (MBNL1, MBNL2 and MBNL3) are highly conserved across vertebrates and are important regulators of RNA alternative splicing. Loss of MBNL protein function through sequestration by CUG or CCUG RNA repeats is largely responsible for the phenotypes of the human geneti...

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Detalles Bibliográficos
Autores principales: Hinman, Melissa N., Richardson, Jared I., Sockol, Rose A., Aronson, Eliza D., Stednitz, Sarah J., Murray, Katrina N., Berglund, J. Andrew, Guillemin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246264/
https://www.ncbi.nlm.nih.gov/pubmed/34125183
http://dx.doi.org/10.1242/dmm.045773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246264/
https://www.ncbi.nlm.nih.gov/pubmed/34125183
http://dx.doi.org/10.1242/dmm.045773

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