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Ronin overexpression induces cerebellar degeneration in a mouse model of ataxia

Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous inherited neurodegenerative disorders characterized by progressive ataxia and cerebellar degeneration. Here, we used a mouse model to test a possible connection between SCA and Ronin (Thap11), a polyglutamine-containing transcri...

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Detalles Bibliográficos
Autores principales: Zwaka, Thomas P., Skowronska, Marta, Richman, Ronald, Dejosez, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246265/
https://www.ncbi.nlm.nih.gov/pubmed/34165550
http://dx.doi.org/10.1242/dmm.044834