Loss of p21-activated kinase Mbt/PAK4 causes Parkinson-like phenotypes in Drosophila

Parkinson's disease (PD) provokes bradykinesia, resting tremor, rigidity and postural instability, and also non-motor symptoms such as depression, anxiety, sleep and cognitive impairments. Similar phenotypes can be induced in Drosophila melanogaster through modification of PD-relevant genes or...

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Detalles Bibliográficos
Autores principales: Pütz, Stephanie M., Kram, Jette, Rauh, Elisa, Kaiser, Sophie, Toews, Romy, Lueningschroer-Wang, Yi, Rieger, Dirk, Raabe, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246267/
https://www.ncbi.nlm.nih.gov/pubmed/34125184
http://dx.doi.org/10.1242/dmm.047811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246267/
https://www.ncbi.nlm.nih.gov/pubmed/34125184
http://dx.doi.org/10.1242/dmm.047811

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