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Loss of p21-activated kinase Mbt/PAK4 causes Parkinson-like phenotypes in Drosophila
Parkinson's disease (PD) provokes bradykinesia, resting tremor, rigidity and postural instability, and also non-motor symptoms such as depression, anxiety, sleep and cognitive impairments. Similar phenotypes can be induced in Drosophila melanogaster through modification of PD-relevant genes or...
Autores principales: | Pütz, Stephanie M., Kram, Jette, Rauh, Elisa, Kaiser, Sophie, Toews, Romy, Lueningschroer-Wang, Yi, Rieger, Dirk, Raabe, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246267/ https://www.ncbi.nlm.nih.gov/pubmed/34125184 http://dx.doi.org/10.1242/dmm.047811 |
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