Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis

The asymmetric distribution of phosphatidylserine (PS) in the cytoplasmic leaflet of eukaryotic cell plasma membranes is regulated by a group of P4-ATPases (named PS flippases) and the β-subunit TMEM30A. Podocytes in the glomerulus form a filtration barrier to prevent the traversing of large cellula...

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Detalles Bibliográficos
Autores principales: Liu, Wenjing, Peng, Lei, Tian, Wanli, Li, Yi, Zhang, Ping, Sun, Kuanxiang, Yang, Yeming, Li, Xiao, Li, Guisen, Zhu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246268/
https://www.ncbi.nlm.nih.gov/pubmed/34080006
http://dx.doi.org/10.1242/dmm.048777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246268/
https://www.ncbi.nlm.nih.gov/pubmed/34080006
http://dx.doi.org/10.1242/dmm.048777

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