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Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis
The asymmetric distribution of phosphatidylserine (PS) in the cytoplasmic leaflet of eukaryotic cell plasma membranes is regulated by a group of P4-ATPases (named PS flippases) and the β-subunit TMEM30A. Podocytes in the glomerulus form a filtration barrier to prevent the traversing of large cellula...
Autores principales: | Liu, Wenjing, Peng, Lei, Tian, Wanli, Li, Yi, Zhang, Ping, Sun, Kuanxiang, Yang, Yeming, Li, Xiao, Li, Guisen, Zhu, Xianjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246268/ https://www.ncbi.nlm.nih.gov/pubmed/34080006 http://dx.doi.org/10.1242/dmm.048777 |
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