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Glycan–protein cross-linking mass spectrometry reveals sialic acid-mediated protein networks on cell surfaces

A cross-linking method is developed to elucidate glycan-mediated interactions between membrane proteins through sialic acids. The method provides information on previously unknown extensive glycomic interactions on cell membranes. The vast majority of membrane proteins are glycosylated with complica...

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Detalles Bibliográficos
Autores principales: Xie, Yixuan, Chen, Siyu, Li, Qiongyu, Sheng, Ying, Alvarez, Michael Russelle, Reyes, Joeriggo, Xu, Gege, Solakyildirim, Kemal, Lebrilla, Carlito B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246274/
https://www.ncbi.nlm.nih.gov/pubmed/34257876
http://dx.doi.org/10.1039/d1sc00814e