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Target-based drug discovery, ADMET profiling and bioactivity studies of antibiotics as potential inhibitors of SARS-CoV-2 main protease (M(pro))

A recent outbreak of a new strain of Coronavirus (SARS-CoV-2) has become a global health burden, which has resulted in deaths. No proven drug has been found to effectively cure this fast-spreading infection, hence the need to explore old drugs with the known profile in tackling this pandemic. A comp...

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Detalles Bibliográficos
Autores principales: Abdul-Hammed, Misbaudeen, Adedotun, Ibrahim Olaide, Falade, Victoria Adeola, Adepoju, Adewusi John, Olasupo, Sabitu Babatunde, Akinboade, Modinat Wuraola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246438/
https://www.ncbi.nlm.nih.gov/pubmed/34226871
http://dx.doi.org/10.1007/s13337-021-00717-z