Adeno-associated Virus Virus-like Particle Characterization via Orthogonal Methods: Nanoelectrospray Differential Mobility Analysis, Asymmetric Flow Field-Flow Fractionation, and Atomic Force Microscopy

[Image: see text] Adeno-associated virus (AAV)-based virus-like particles (VLPs) are thriving vectors of choice in the biopharmaceutical field of gene therapy. Here, a method to investigate purified AAV serotype 8 (AAV8) batches via a nanoelectrospray gas-phase mobility molecular analyzer (nES GEMMA...

Descripción completa

Detalles Bibliográficos
Autores principales: Zoratto, Samuele, Weiss, Victor U., Friedbacher, Gernot, Buengener, Carsten, Pletzenauer, Robert, Foettinger-Vacha, Alexandra, Graninger, Michael, Allmaier, Guenter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246466/
https://www.ncbi.nlm.nih.gov/pubmed/34235314
http://dx.doi.org/10.1021/acsomega.1c01443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246466/
https://www.ncbi.nlm.nih.gov/pubmed/34235314
http://dx.doi.org/10.1021/acsomega.1c01443

Ejemplares similares