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Adeno-associated Virus Virus-like Particle Characterization via Orthogonal Methods: Nanoelectrospray Differential Mobility Analysis, Asymmetric Flow Field-Flow Fractionation, and Atomic Force Microscopy

[Image: see text] Adeno-associated virus (AAV)-based virus-like particles (VLPs) are thriving vectors of choice in the biopharmaceutical field of gene therapy. Here, a method to investigate purified AAV serotype 8 (AAV8) batches via a nanoelectrospray gas-phase mobility molecular analyzer (nES GEMMA...

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Detalles Bibliográficos
Autores principales:	Zoratto, Samuele, Weiss, Victor U., Friedbacher, Gernot, Buengener, Carsten, Pletzenauer, Robert, Foettinger-Vacha, Alexandra, Graninger, Michael, Allmaier, Guenter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246466/ https://www.ncbi.nlm.nih.gov/pubmed/34235314 http://dx.doi.org/10.1021/acsomega.1c01443

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