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Emulating the gut–liver axis: Dissecting the microbiome's effect on drug metabolism using multiorgan-on-chip models

The homeostatic relationship between the gut, its microbiome, and the liver is crucial for the regulation of drug metabolism processes. Gut microbes are known to influence human health and disease by enhancing food metabolism and providing a first line of defense against pathogens. In addition to th...

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Detalles Bibliográficos
Autores principales: Lucchetti, Mara, Kaminska, Mathilda, Oluwasegun, Aina Kehinde, Mosig, Alexander S., Wilmes, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246515/
https://www.ncbi.nlm.nih.gov/pubmed/34239997
http://dx.doi.org/10.1016/j.coemr.2021.03.003