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Emulating the gut–liver axis: Dissecting the microbiome's effect on drug metabolism using multiorgan-on-chip models
The homeostatic relationship between the gut, its microbiome, and the liver is crucial for the regulation of drug metabolism processes. Gut microbes are known to influence human health and disease by enhancing food metabolism and providing a first line of defense against pathogens. In addition to th...
Autores principales: | Lucchetti, Mara, Kaminska, Mathilda, Oluwasegun, Aina Kehinde, Mosig, Alexander S., Wilmes, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246515/ https://www.ncbi.nlm.nih.gov/pubmed/34239997 http://dx.doi.org/10.1016/j.coemr.2021.03.003 |
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