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Mitochondrial ion channels in pancreatic β‐cells: Novel pharmacological targets for the treatment of Type 2 diabetes

Pancreatic beta‐cells are central regulators of glucose homeostasis. By tightly coupling nutrient sensing and granule exocytosis, beta‐cells adjust the secretion of insulin to the circulating blood glucose levels. Failure of beta‐cells to augment insulin secretion in insulin‐resistant individuals le...

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Detalles Bibliográficos
Autores principales: De Marchi, Umberto, Fernandez‐Martinez, Silvia, de la Fuente, Sergio, Wiederkehr, Andreas, Santo‐Domingo, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246559/
https://www.ncbi.nlm.nih.gov/pubmed/32056196
http://dx.doi.org/10.1111/bph.15018